Current:Home > Biography > Research staff > Prof. Qiong Chen


Qiongyou Wu, Ph.D. Associate Professor
Room 802, College of Chemistry
Central China Normal University
152 Luoyu Road, Wuhan Hubei Province
P. R. China 430079


Office:Chemistry Building, Room 802
Mobile: +86-13871384591


Post Doc. Institute of chemistry, Academia Sinica, Taiwan(2007-2008)
Ph.D.   College of Chemistryand Molecule Sciences, Wuhan University (January 2004)
B.S.     Department of chemistry, Fuyang Normal College (June 1998).


Organic chemistry,Natural product based pesticide discovery


  1. ZuoYang, Yang Sheng-Gang, Luo Yan-Ping, Tan Yin, Hao Ge-Fei, Wu Qiong-You, Zhen Xi, * Guang-Fu Yang. * Design and Synthesis of1-(Benzothiazol-5-yl)-1H-1,2,4-triazol-5-ones as Protoporphyrinogen OxidaseInhibitors.Bioorg. Med. Chem. 2013, 21, 3245-3255.
  2. Lin,L.; Mulholland, N.; Wu, Q. Y.;Beattie, D.; Huang, S. W.; Irwin, D.; Clough, J. Gu, Y. C.; * Yang, G. F. *Synthesis and Antifungal Activity of Novel Sclerotiorin Analogues. J. Agric. Food Chem. 2012, 60, 4480−4491.
  3. Lin,L.; Mulholland, N.; Huang, S. W.; Beattie, D.; Irwin, D.; Gu, Y. C.; Clough,J.; Wu, Q. Y.;* Yang, G. F. Design,Synthesis and Antifungal Activity of Novel Sclerotiorin Derivatives. Chem. Biol. Drug. Des. 2012, 80, 682-692.
  4. Lin,L.; Wu, Q. Y.; * Huang, S. W.; Yang, G. F. * Facile synthesis of3-substituted isoquinolines derivatives via microwave-assisted tandemthree-component coupling cyclization. Chin.J. Chem. 2012, 30, 1075-1082.
  5. Yang Zuo, Sheng-Gang Yang, Li-Li Jiang,Ge-Fei Hao, Zhi-Fang Wang, Qiong-You Wu,Zhen Xi, Guang-Fu Yang. Quantitative strcture-activity relationships of1,3,4-thiadiazole-2(3H)-noes and 1,3,4-oxadiazole-2(3H)-ones as humanprotoporphyrinogen oxidase inhibitors. Bioorg. Med. Chem. 2012,20, 296-304.
  6. Jiang L. L.; Zuo, Y.; Wang, Z. F.; Tan, Y.; Wu Q. Y.; Xi, Z.; Yang, G. F. Design and Synthesesof Novel N-(Benzothiazol-5-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dioneand N-(Benzothiazol-5-yl)isoindoline-1,3-dione as PotentProtoporphyrinogen Oxidase Inhibitors. J. Agric. Food Chem.,2011, 59, 6172–6179.
  7. Wu, Q. Y.; Wang, G. D.; Huang, S. W.; Lin, L.; Yang, G. F. *Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives.Molecules 2010, 15,9024-9034.
  8. Zhang,L.; Tan, Y.; Wang, N. X.; Wu, Q. Y.;Xi, Z.; Yang, G. F. Design, syntheses and 3D-QSAR studies of novel N-phenyl pyrrolidin-2-onesand N-phenyl-1H-pyrrol-2-ones as protoporphyrinogen oxidase inhibitors. Bioorganic & Medicinal Chem. 2010, 18, 7948-7956.
  9. Chen, K. F; Hsu,Y.C.; Wu, Q. Y.; P. Yeh, M. C.; Sun, S. S. Structurally Simple Dipolar Organic Dyes Featuring 1,3-CyclohexadieneConjugated Unit for Dye-Sensitized Solar Cells. Org. Lett. 2009, 11, 377–380.
  10. Wan, J. Q.; Zhu, R. Z.; Xia, Y.; Qu, F. Q.;Wu, Q. Y.; Yang, G. F.; Neyts, J.;Peng, L. Synthesis of 5-aryltriazole ribonucleosides via Suzuki coupling andpromoted by microwave irradiation. Tetrahedron Lett. 2006, 47, 6727-6731.
  11. 赵培亮,吴琼友,周中振,杨光富,微波辐射下以1,3-二溴-5,5-二甲基乙内酰脲为溴代试剂合成3-溴黄酮。有机化学, 2006,26, 694-697.
  12. 陈悟,陈琼,吴琼友,杨光富,含恶二唑杂环取代的新型三唑并嘧啶衍生物的合成及其生物活性,有机化学,2005, 25,1477-1481.
  13. Wu, Q. Y.; Qu, F. Q.; Wan,J. Q.; Xia, Y.; Peng, L. “Photolabeling Probes for Ribavirin andEICAR”Nucleosides Nucleotides and Nucleic Acid 2005, 999-1008.
  14. Wu, Q. Y.; Qu, F. Q.; Wan,J. Q.; Zhu, X.; Xia, Y.; Peng, L. “Design, Synthesis and Characterization ofPhotolabeling Probes for Studying the Mechanisms Underlying the AntiviralEffects of Ribavirin” Helvetica ChimicaActa, 2004, 87, 811-819.
  15. Wu, Q. Y.; Wan, J. Q.; Xia,Y.; Zhou, J. H.; Qu, F. Q.; Peng, L. “Synthesis and Chracterization of Potential Photolabeling Probes forStudying the Antiviral Mechanisms of EICAR”, Heterocycles, 2004,63, 671-679.
  16. Wu, Q. Y.; Zhu, X.; Wan, J.Q.; Qu, F. Q.; Peng, L. “Synthesis of a Photolabeling Probe for theMechanism Study of Ribavirin”, ChineseChem. Lett., 2004, 15,907-910.

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Key Laboratory of Pesticide & Chemical Biology of Ministry of Education
College of Chemistry · Central China Normal University

Last update: Aug 20, 2016 · By: Chengzhang Li