| ID LINK | NAME | STRUCTURE CAS | CLOGP | CLOGS | MW | THERAPEUTIC AREA |
|---|---|---|---|---|---|---|
| FDBD00001 | Bivalirudin |
 128270-60-0 |
0.055 | -8.581 | 2180.285 | For treatment of heparin-induced thrombocytopenia and for the prevention of thrombosis. |
| FDBD00002 | Goserelin |
 65807-02-5 |
1.363 | -8.643 | 1269.410 | Used to treat hormone-sensitive cancers of the breast (in pre- and peri- menopausal women) and prostate, and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, goserelin is used in assisted reproduction and in the treatment of precocious puberty. |
| FDBD00003 | Desmopressin |
 16679-58-6 |
-1.776 | -6.711 | 1069.217 | Oral formulations may be used to manage primary nocturnal enuresis in adults and vasopressin sensitive diabetes insipidus, and for control of temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. Intranasal and parenteral formulations may be used to manage spontaneous or trauma-induced bleeds (e.g. hemarthrosis, intramuscular hematoma, mucosal bleeding) in patients with hemophilia A or von Willebrand's disease Type I. May also be used parenterally to prevent or treat bleeding in patients with uremia. |
| FDBD00004 | Cetrorelix |
 120287-85-6 |
4.460 | -12.132 | 1431.038 | For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation. |
| FDBD00005 | Cyclosporine |
 59865-13-3 |
5.419 | -6.417 | 1202.611 | For treatment of transplant (kidney, liver, and heart) rejection, rheumatoid arthritis, severe psoriasis. |
| FDBD00006 | Felypressin |
 56-59-7 |
-1.358 | -6.858 | 1040.219 | For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential. |
| FDBD00007 | Octreotide |
 83150-76-9 |
2.243 | -8.995 | 1019.239 | For treatment of acromegaly and reduction of side effects from cancer chemotherapy. |
| FDBD00009 | Tetrahydrofolic acid |
 135-16-0 |
-0.610 | -3.479 | 445.429 | For nutritional supplementation, also for treating dietary shortage or imbalance. |
| FDBD00010 | L-Histidine |
 71-00-1 |
-0.063 | -0.386 | 155.155 | The actions of supplemental L-histidine are entirely unclear. It may have some immunomodulatory as well as antioxidant activity. L-histidine may be indicated for use in some with rheumatoid arthritis. It is not indicated for treatment of anemia or uremia or for lowering serum cholesterol. |
| FDBD00011 | S-Adenosylmethionine |
 29908-03-0 |
-3.372 | -0.159 | 399.445 | For the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis.Also as a dietary supplement for the support of bone and joint health, as well as mood and emotional well being. |
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