IUPAC name
(2R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane]
SMILES
CC1O[C@@]2(CS1)CN1CCC2CC1
Compound class
Parasympathomimetics; Nervous System; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors;
Therapeutic area
For the treatment of symptoms of dry mouth in patients with Sjögren's Syndrome.
Common name
Cevimeline
IUPAC name
(2R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane]
SMILES
CC1O[C@@]2(CS1)CN1CCC2CC1
INCHI
InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8?,10-/m1/s1
FORMULA
C10H17NOS
Common name
Cevimeline
IUPAC name
(2R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane]
Molecular weight
199.313
clogP
1.837
clogS
-1.477
HBond Acceptor
2
HBond Donor
0
Total Polar Surface Area
37.77
Number of Rings
3
Rotatable Bond
0
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00210 | (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-quinuclidine] |
|
S1CC2(OC1C)C3CCN(C2)CC3 | 0.0003 |
1 ,
1
