IUPAC name
7-chloro-5-(2-chlorophenyl)-3-hydroxy-2,3-dihydro-1H-1,4-benzodiazepin-2-one
SMILES
OC1N=C(C2=CC=CC=C2Cl)C2=C(NC1=O)C=CC(Cl)=C2
Compound class
Anti-Anxiety Agents; Hypnotics and Sedatives; Anticonvulsants; GABA Modulators; Antiemetics; Benzodiazepines; Nervous System; Benzodiazepine Derivatives; Anxiolytics; Psycholeptics;
Therapeutic area
For the management of anxiety disorders, and for treatment of status epilepticus.
Common name
Lorazepam
IUPAC name
7-chloro-5-(2-chlorophenyl)-3-hydroxy-2,3-dihydro-1H-1,4-benzodiazepin-2-one
SMILES
OC1N=C(C2=CC=CC=C2Cl)C2=C(NC1=O)C=CC(Cl)=C2
INCHI
InChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)
FORMULA
C15H10Cl2N2O2
Common name
Lorazepam
IUPAC name
7-chloro-5-(2-chlorophenyl)-3-hydroxy-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Molecular weight
321.158
clogP
3.915
clogS
-5.064
HBond Acceptor
3
HBond Donor
2
Total Polar Surface Area
61.69
Number of Rings
3
Rotatable Bond
1
