IUPAC name
4-(4-aminobenzenesulfonyl)aniline
SMILES
NC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(N)C=C1
Compound class
Antimalarials; Folic Acid Antagonists; Anti-Infective Agents; Leprostatic Agents; Anti-Acne Preparations; Antimycobacterials; Antiinfectives for Systemic Use; Dermatologicals; Anti-Acne Preparations for Topical Use; Drugs for Treatment of Lepra; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors;
Therapeutic area
For the treatment and management of leprosy and dermatitis herpetiformis.
Common name
Dapsone
IUPAC name
4-(4-aminobenzenesulfonyl)aniline
SMILES
NC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(N)C=C1
INCHI
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
FORMULA
C12H12N2O2S
Common name
Dapsone
IUPAC name
4-(4-aminobenzenesulfonyl)aniline
Molecular weight
248.301
clogP
0.846
clogS
-2.916
HBond Acceptor
2
HBond Donor
4
Total Polar Surface Area
86.18
Number of Rings
2
Rotatable Bond
2
