IUPAC name
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
SMILES
N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C=C2)C(I)=C1)C(O)=O
Compound class
Hormone Replacement Agents; Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins; Thyroid Hormones; Thyroid Preparations; Thyroid Therapy;
Therapeutic area
Used as replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyrodism during the recovery phase of subacute thyroiditis.
Common name
Liothyronine
IUPAC name
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
SMILES
N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C=C2)C(I)=C1)C(O)=O
INCHI
InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1
FORMULA
C15H12I3NO4
Common name
Liothyronine
IUPAC name
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
Molecular weight
650.973
clogP
4.581
clogS
-5.269
HBond Acceptor
4
HBond Donor
4
Total Polar Surface Area
92.78
Number of Rings
2
Rotatable Bond
5
