IUPAC name
(1S,5R,13R,14S,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0
SMILES
[H][C@@]12OC3=C(OC)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])C=C[C@@H]2O
Compound class
Analgesics; Analgesics, Opioid; Narcotics; Antitussive Agents; Cough and Cold Preparations; Respiratory System; Nervous System; Opioids; Natural Opium Alkaloids; Opium Alkaloids and Derivatives; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors;
Therapeutic area
For treatment and management of pain (systemic). It is also used as an antidiarrheal and as a cough suppressant.
Common name
Codeine
IUPAC name
(1S,5R,13R,14S,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0
SMILES
[H][C@@]12OC3=C(OC)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])C=C[C@@H]2O
INCHI
InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1
FORMULA
C18H21NO3
Common name
Codeine
IUPAC name
(1S,5R,13R,14S,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0
Molecular weight
299.364
clogP
1.859
clogS
-2.461
HBond Acceptor
4
HBond Donor
1
Total Polar Surface Area
41.93
Number of Rings
5
Rotatable Bond
1
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00721 | methylBLAHol |
|
O1C2C34C(C(N(CC3)C)Cc5c4c1ccc5)C=CC2O | 0.0010 |
