Responsive image

Common name


Norepinephrine

IUPAC name


4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol

SMILES


NC[C@H](O)C1=CC(O)=C(O)C=C1

Compound class


Vasoconstrictor Agents; Sympathomimetics; Adrenergic alpha-Agonists; Cardiovascular System; Cardiac Therapy; Adrenergic and Dopaminergic Agents; Cardiac Stimulants Excl. Cardiac Glycosides; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Beta2 Agonists; Alpha2 Agonists;

Therapeutic area


Mainly used to treat patients in vasodilatory shock states such as septic shock and neurogenic shock and has shown a survival benefit over dopamine. Also used as a vasopressor medication for patients with critical hypotension.

Common name


Norepinephrine

IUPAC name


4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol

SMILES


NC[C@H](O)C1=CC(O)=C(O)C=C1

INCHI


InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1

FORMULA


C8H11NO3

Responsive image

Common name


Norepinephrine

IUPAC name


4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol

Molecular weight


169.178

clogP


0.023

clogS


-0.306

HBond Acceptor


3

HBond Donor


5

Total Polar
Surface Area


86.71

Number of Rings


1

Rotatable Bond


2

Drug ID Common name Structure CAS SMILE Frequency
FDBF00203 benzene-1,2-diol Responsive image c1cc(c(cc1)O)O 0.0079
2 , 1