IUPAC name
6-phenylpteridine-2,4,7-triamine
SMILES
NC1=NC(N)=C2N=C(C(N)=NC2=N1)C1=CC=CC=C1
Compound class
Diuretics; Epithelial Sodium Channel Blockers; Cardiovascular System; Potassium-Sparing Agents; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers;
Therapeutic area
For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and the nephrotic syndrome; also in steroid-induced edema, idiopathic edema, and edema due to secondary hyperaldosteronism.
Common name
Triamterene
IUPAC name
6-phenylpteridine-2,4,7-triamine
SMILES
NC1=NC(N)=C2N=C(C(N)=NC2=N1)C1=CC=CC=C1
INCHI
InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)
FORMULA
C12H11N7
Common name
Triamterene
IUPAC name
6-phenylpteridine-2,4,7-triamine
Molecular weight
253.263
clogP
0.182
clogS
-3.272
HBond Acceptor
4
HBond Donor
6
Total Polar Surface Area
129.62
Number of Rings
3
Rotatable Bond
1
