IUPAC name
1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol
SMILES
OC(CCN1CCCC1)(C1CCCCC1)C1=CC=CC=C1
Compound class
Antiparkinson Agents; Muscarinic Antagonists; Antidyskinetics; Nervous System; Anti-Parkinson Drugs; Anticholinergics; Tertiary Amines;
Therapeutic area
For the treatment of all forms of Parkinson's Disease, as well as control of extrapyramidal reactions induced by antipsychotic agents.
Common name
Procyclidine
IUPAC name
1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol
SMILES
OC(CCN1CCCC1)(C1CCCCC1)C1=CC=CC=C1
INCHI
InChI=1S/C19H29NO/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2
FORMULA
C19H29NO
Common name
Procyclidine
IUPAC name
1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol
Molecular weight
287.440
clogP
3.993
clogS
-3.800
HBond Acceptor
2
HBond Donor
1
Total Polar Surface Area
23.47
Number of Rings
3
Rotatable Bond
5
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00209 | 1-methylpyrrolidine |
|
N1(CCCC1)C | 0.0076 |
| FDBF00394 | cyclohexylmethanol |
|
C1(CCCCC1)CO | 0.0021 |
| FDBF00690 | pyrrolidine |
|
N1CCCC1 | 0.0072 |
| FDBF00827 | (1R)-1-cyclohexylethanol |
|
CC(C1CCCCC1)O | 0.0007 |
| FDBF00828 | (1R)-1-cyclohexylpropan-1-ol |
|
C(C)C(C1CCCCC1)O | 0.0007 |
| FDBF00847 | 1-ethylpyrrolidine |
|
CCN1CCCC1 | 0.0027 |
7 ,
1
