Responsive image

Common name


Phenylephrine

IUPAC name


3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol

SMILES


CNC[C@H](O)C1=CC(O)=CC=C1

Compound class


Vasoconstrictor Agents; Sympathomimetics; Adrenergic alpha-1 Receptor Agonists; Cardiotonic Agents; Mydriatics; Nasal Decongestants; Respiratory System; Ophthalmologicals; Sensory Organs; Nasal Preparations; Cardiovascular System; Cardiac Therapy; Adrenergic and Dopaminergic Agents; Cardiac Stimulants Excl. Cardiac Glycosides; Sympathomimetics, Plain; Nasal Decongestants for Systemic Use; Sympathomimetics Excl. Antiglaucoma Preparations; Mydriatics and Cycloplegics; Sympathomimetics Used as Decongestants; Decongestants and Antiallergics; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers;

Therapeutic area


Phenylephrine is mainly used to treat nasal congestion, but may also be useful in treating hypotension and shock, hypotension during spinal anaesthesia, prolongation of spinal anaesthesia, paroxysmal supraventricular tachycardia, symptomatic relief of external or internal hemorrhoids, and to increase blood pressure as an aid in the diagnosis of heart murmurs.

Common name


Phenylephrine

IUPAC name


3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol

SMILES


CNC[C@H](O)C1=CC(O)=CC=C1

INCHI


InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m0/s1

FORMULA


C9H13NO2

Responsive image

Common name


Phenylephrine

IUPAC name


3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol

Molecular weight


167.205

clogP


0.905

clogS


-1.527

HBond Acceptor


2

HBond Donor


3

Total Polar
Surface Area


52.49

Number of Rings


1

Rotatable Bond


3

Drug ID Common name Structure CAS SMILE Frequency
FDBF00006 phenol Responsive image c1ccc(cc1)O 0.0897
FDBF00041 ethanol Responsive image CCO 0.1474
FDBF00066 N-methylmethanamine Responsive image N(C)C 0.0914
FDBF00287 2-(methylamino)ethanol Responsive image C(CO)NC 0.0089
FDBF00848 3-(hydroxymethyl)phenol Responsive image c1(cc(ccc1)O)CO 0.0017
FDBF00849 3-[(1S)-1-hydroxyethyl]phenol Responsive image c1(cc(ccc1)O)C(C)O 0.0003
6 , 1