
IUPAC name
3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol
SMILES
CNC[C@H](O)C1=CC(O)=CC=C1
Compound class
Vasoconstrictor Agents; Sympathomimetics; Adrenergic alpha-1 Receptor Agonists; Cardiotonic Agents; Mydriatics; Nasal Decongestants; Respiratory System; Ophthalmologicals; Sensory Organs; Nasal Preparations; Cardiovascular System; Cardiac Therapy; Adrenergic and Dopaminergic Agents; Cardiac Stimulants Excl. Cardiac Glycosides; Sympathomimetics, Plain; Nasal Decongestants for Systemic Use; Sympathomimetics Excl. Antiglaucoma Preparations; Mydriatics and Cycloplegics; Sympathomimetics Used as Decongestants; Decongestants and Antiallergics; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers;
Therapeutic area
Phenylephrine is mainly used to treat nasal congestion, but may also be useful in treating hypotension and shock, hypotension during spinal anaesthesia, prolongation of spinal anaesthesia, paroxysmal supraventricular tachycardia, symptomatic relief of external or internal hemorrhoids, and to increase blood pressure as an aid in the diagnosis of heart murmurs.
Common name
Phenylephrine
IUPAC name
3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol
SMILES
CNC[C@H](O)C1=CC(O)=CC=C1
INCHI
InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m0/s1
FORMULA
C9H13NO2

Common name
Phenylephrine
IUPAC name
3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol
Molecular weight
167.205
clogP
0.905
clogS
-1.527
HBond Acceptor
2
HBond Donor
3
Total Polar Surface Area
52.49
Number of Rings
1
Rotatable Bond
3
Drug ID | Common name | Structure CAS | SMILE | Frequency |
---|---|---|---|---|
FDBF00006 | phenol |
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c1ccc(cc1)O | 0.0897 |
FDBF00041 | ethanol |
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CCO | 0.1474 |
FDBF00066 | N-methylmethanamine |
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N(C)C | 0.0914 |
FDBF00287 | 2-(methylamino)ethanol |
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C(CO)NC | 0.0089 |
FDBF00848 | 3-(hydroxymethyl)phenol |
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c1(cc(ccc1)O)CO | 0.0017 |
FDBF00849 | 3-[(1S)-1-hydroxyethyl]phenol |
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c1(cc(ccc1)O)C(C)O | 0.0003 |