IUPAC name
2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine
SMILES
CC1=CC=C(C=C1)C(=C/CN1CCCC1)\C1=CC=CC=N1
Compound class
Anti-Allergic Agents; Histamine H1 Antagonists; Respiratory System; Antihistamines for Systemic Use; CYP2D6 Inducers; CYP2D6 Inducers (strong);
Therapeutic area
For the symptomatic relief of seasonal or perennial allergic rhinitis or nonallergic rhinitis; allergic conjunctivitis; and mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Also used in combination with other agents for the symptomatic relief of symptoms associated with the common cold.
Common name
Triprolidine
IUPAC name
2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine
SMILES
CC1=CC=C(C=C1)C(=C/CN1CCCC1)\C1=CC=CC=N1
INCHI
InChI=1S/C19H22N2/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21/h2-3,6-12H,4-5,13-15H2,1H3/b18-11+
FORMULA
C19H22N2
Common name
Triprolidine
IUPAC name
2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine
Molecular weight
278.391
clogP
4.450
clogS
-4.656
HBond Acceptor
2
HBond Donor
0
Total Polar Surface Area
16.13
Number of Rings
3
Rotatable Bond
4
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00014 | pyridine |
|
c1cccnc1 | 0.0333 |
| FDBF00022 | prop-1-ene |
|
CC=C | 0.0299 |
| FDBF00023 | toluene |
|
c1(ccccc1)C | 0.1268 |
| FDBF00209 | 1-methylpyrrolidine |
|
N1(CCCC1)C | 0.0076 |
| FDBF00690 | pyrrolidine |
|
N1CCCC1 | 0.0072 |
| FDBF00928 | 2-vinylpyridine |
|
n1c(cccc1)C=C | 0.0010 |
| FDBF00929 | 1-allylpyrrolidine |
|
N1(CCCC1)CC=C | 0.0014 |
| FDBF00930 | 2-[(E)-prop-1-enyl]pyridine |
|
n1c(cccc1)C=CC | 0.0007 |
| FDBF00931 | 2-[(E)-3-pyrrolidin-1-ylprop-1-enyl]pyridine |
|
n1c(cccc1)C=CCN2CCCC2 | 0.0007 |
