IUPAC name
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
SMILES
CN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(Cl)C=C3)CC1
Compound class
Antipsychotic Agents; Antiemetics; Dopamine Antagonists; Phenothiazines; Nervous System; Psycholeptics; Phenothiazines With Piperazine Structure; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors;
Therapeutic area
For the symptomatic management of psychotic disorders, short term management of nonpsychotic anxiety in patients with generalized anxiety disorder, and for the control of severe nausea and vomiting of various causes.
Common name
Prochlorperazine
IUPAC name
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
SMILES
CN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(Cl)C=C3)CC1
INCHI
InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3
FORMULA
C20H24ClN3S
Common name
Prochlorperazine
IUPAC name
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
Molecular weight
373.943
clogP
3.853
clogS
-5.237
HBond Acceptor
3
HBond Donor
0
Total Polar
Surface Area
35.02
Number of Rings
4
Rotatable Bond
4
