IUPAC name
(1S,9R,10S)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.0¹,¹
SMILES
[H][C@@]12CC3=C(C=C(O)C=C3)[C@]3(CCCC[C@@]13O)CCN2CC1CCC1
Compound class
Analgesics; Analgesics, Opioid; Narcotics; Antitussive Agents; Narcotic Antagonists; Cough and Cold Preparations; Respiratory System; Nervous System; Opioids; Opium Alkaloids and Derivatives; Morphinan Derivatives;
Therapeutic area
For the relief of moderate to severe pain.
Common name
Butorphanol
IUPAC name
(1S,9R,10S)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.0¹,¹
SMILES
[H][C@@]12CC3=C(C=C(O)C=C3)[C@]3(CCCC[C@@]13O)CCN2CC1CCC1
INCHI
InChI=1S/C21H29NO2/c23-17-7-6-16-12-19-21(24)9-2-1-8-20(21,18(16)13-17)10-11-22(19)14-15-4-3-5-15/h6-7,13,15,19,23-24H,1-5,8-12,14H2/t19-,20+,21+/m0/s1
FORMULA
C21H29NO2
Common name
Butorphanol
IUPAC name
(1S,9R,10S)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.0¹,¹
Molecular weight
327.460
clogP
3.594
clogS
-3.903
HBond Acceptor
3
HBond Donor
2
Total Polar Surface Area
43.7
Number of Rings
5
Rotatable Bond
2
