Responsive image

Common name


Chlorpropamide

IUPAC name


1-(4-chlorobenzenesulfonyl)-3-propylurea

SMILES


CCCNC(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1

Compound class


Hypoglycemic Agents; Antidiabetic Agents; Drugs Used in Diabetes; Alimentary Tract and Metabolism; Blood Glucose Lowering Drugs, Excl. Insulins; Sulfonylureas; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers;

Therapeutic area


For treatment of NIDDM in conjunction with diet and exercise.

Common name


Chlorpropamide

IUPAC name


1-(4-chlorobenzenesulfonyl)-3-propylurea

SMILES


CCCNC(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1

INCHI


InChI=1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)

FORMULA


C10H13ClN2O3S

Responsive image

Common name


Chlorpropamide

IUPAC name


1-(4-chlorobenzenesulfonyl)-3-propylurea

Molecular weight


276.740

clogP


0.861

clogS


-3.581

HBond Acceptor


3

HBond Donor


2

Total Polar
Surface Area


75.27

Number of Rings


1

Rotatable Bond


4

Drug ID Common name Structure CAS SMILE Frequency
FDBF00007 propane Responsive image C(C)C 0.2412
FDBF00016 chlorobenzene Responsive image c1ccc(cc1)Cl 0.0718
2 , 1