IUPAC name
ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate
SMILES
CCOC(=O)NC1=CC2=C(SC3=CC=CC=C3N2C(=O)CCN2CCOCC2)C=C1
Compound class
Anti-Arrhythmia Agents; Voltage-Gated Sodium Channel Blockers; Cardiovascular System; Antiarrhythmics, Class I and Iii; Cardiac Therapy; Antiarrythmics, Class I and Iii;
Therapeutic area
Used to treat irregular heartbeats (arrhythmias) and maintain a normal heart rate.
Common name
Moricizine
IUPAC name
ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate
SMILES
CCOC(=O)NC1=CC2=C(SC3=CC=CC=C3N2C(=O)CCN2CCOCC2)C=C1
INCHI
InChI=1S/C22H25N3O4S/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24/h3-8,15H,2,9-14H2,1H3,(H,23,27)
FORMULA
C22H25N3O4S
Common name
Moricizine
IUPAC name
ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate
Molecular weight
427.517
clogP
2.724
clogS
-4.669
HBond Acceptor
5
HBond Donor
1
Total Polar Surface Area
96.41
Number of Rings
4
Rotatable Bond
7
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00484 | morpholine |
|
O1CCNCC1 | 0.0082 |
| FDBF00710 | 4-methylmorpholine |
|
O1CCN(CC1)C | 0.0052 |
| FDBF00714 | 4-ethylmorpholine |
|
O1CCN(CC1)CC | 0.0031 |
| FDBF00906 | ethyl carbamate |
|
CCOC(=O)N | 0.0055 |
| FDBF01585 | 1-phenothiazin-10-ylethanone |
|
CC(=O)N1c2c(cccc2)Sc3c1cccc3 | 0.0003 |
| FDBF01586 | phenothiazine-10-carbaldehyde |
|
S1c2c(cccc2)N(c3c1cccc3)C=O | 0.0003 |
