IUPAC name
methyl(naphthalen-1-ylmethyl)(3-phenylprop-2-en-1-yl)amine
SMILES
CN(CC=CC1=CC=CC=C1)CC1=CC=CC2=CC=CC=C12
Compound class
Antifungal Agents; Dermatologicals; Antifungals for Topical Use; Antifungals for Dermatological Use;
Therapeutic area
For the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms .
Common name
Naftifine
IUPAC name
methyl(naphthalen-1-ylmethyl)(3-phenylprop-2-en-1-yl)amine
SMILES
CN(CC=CC1=CC=CC=C1)CC1=CC=CC2=CC=CC=C12
INCHI
InChI=1S/C21H21N/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20/h2-15H,16-17H2,1H3
FORMULA
C21H21N
Common name
Naftifine
IUPAC name
methyl(naphthalen-1-ylmethyl)(3-phenylprop-2-en-1-yl)amine
Molecular weight
287.398
clogP
5.012
clogS
-5.391
HBond Acceptor
1
HBond Donor
0
Total Polar Surface Area
3.24
Number of Rings
3
Rotatable Bond
5
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00022 | prop-1-ene |
|
CC=C | 0.0299 |
| FDBF00064 | N,N-dimethylmethanamine |
|
N(C)(C)C | 0.0371 |
| FDBF01017 | styrene |
|
C(=C)c1ccccc1 | 0.0041 |
| FDBF01217 | [(E)-prop-1-enyl]benzene |
|
C(=CC)c1ccccc1 | 0.0021 |
| FDBF01707 | N-methylprop-2-en-1-amine |
|
C(NC)C=C | 0.0010 |
| FDBF01709 | N,N-dimethylprop-2-en-1-amine |
|
C(N(C)C)C=C | 0.0007 |
| FDBF01710 | (E)-N-methyl-3-phenyl-prop-2-en-1-amine |
|
C(NC)C=Cc1ccccc1 | 0.0003 |
| FDBF01711 | (E)-N,N-dimethyl-3-phenyl-prop-2-en-1-amine |
|
C(N(C)C)C=Cc1ccccc1 | 0.0003 |
11 ,
2
