IUPAC name
6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
SMILES
NC1=NC2=C(S1)C=C(OC(F)(F)F)C=C2
Compound class
Anticonvulsants; Neuroprotective Agents; Excitatory Amino Acid Antagonists; Nervous System; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers;
Therapeutic area
For the treatment of amyotrophic lateral sclerosis (ALS, Lou Gehrig's Disease).
Common name
Riluzole
IUPAC name
6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
SMILES
NC1=NC2=C(S1)C=C(OC(F)(F)F)C=C2
INCHI
InChI=1S/C8H5F3N2OS/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5/h1-3H,(H2,12,13)
FORMULA
C8H5F3N2OS
Common name
Riluzole
IUPAC name
6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
Molecular weight
234.198
clogP
2.926
clogS
-2.791
HBond Acceptor
2
HBond Donor
2
Total Polar Surface Area
76.38
Number of Rings
2
Rotatable Bond
2
