Responsive image

Common name


Carbinoxamine

IUPAC name


{2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}dimethylamine

SMILES


CN(C)CCOC(C1=CC=C(Cl)C=C1)C1=CC=CC=N1

Compound class


Histamine H1 Antagonists; Histamine Antagonists; Respiratory System; Aminoalkyl Ethers; Antihistamines for Systemic Use; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors;

Therapeutic area


For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis, as well as allergic conjunctivitis caused by foods and inhaled allergens. Also for the relief of allergic reactions to blood or plasma, and the symptomatic management of mild, uncomplicated allergic skin manifestations of urticaria and angioedema.

Common name


Carbinoxamine

IUPAC name


{2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}dimethylamine

SMILES


CN(C)CCOC(C1=CC=C(Cl)C=C1)C1=CC=CC=N1

INCHI


InChI=1S/C16H19ClN2O/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13/h3-10,16H,11-12H2,1-2H3

FORMULA


C16H19ClN2O

Responsive image

Common name


Carbinoxamine

IUPAC name


{2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}dimethylamine

Molecular weight


290.788

clogP


3.536

clogS


-4.650

HBond Acceptor


3

HBond Donor


0

Total Polar
Surface Area


25.36

Number of Rings


2

Rotatable Bond


6

Drug ID Common name Structure CAS SMILE Frequency
FDBF00014 pyridine Responsive image c1cccnc1 0.0333
FDBF00066 N-methylmethanamine Responsive image N(C)C 0.0914
FDBF00158 methoxymethane Responsive image COC 0.0374
FDBF00168 methoxyethane Responsive image CCOC 0.0254
FDBF00205 1-chloro-4-methyl-benzene Responsive image Cc1ccc(cc1)Cl 0.0113
FDBF01725 (4-chlorophenyl)methanol Responsive image OCc1ccc(cc1)Cl 0.0017
FDBF01730 2-(ethoxymethyl)pyridine Responsive image n1c(cccc1)COCC 0.0007
17 , 2