Responsive image

Common name


Ethotoin

IUPAC name


3-ethyl-5-phenylimidazolidine-2,4-dione

SMILES


CCN1C(=O)NC(C1=O)C1=CC=CC=C1

Compound class


Anticonvulsants; Nervous System; Antiepileptics; Hydantoin Derivatives; Cytochrome P-450 CYP2C19 Inducers;

Therapeutic area


For the control of tonic-clonic (grand mal) and complex partial (psychomotor) seizures.

Common name


Ethotoin

IUPAC name


3-ethyl-5-phenylimidazolidine-2,4-dione

SMILES


CCN1C(=O)NC(C1=O)C1=CC=CC=C1

INCHI


InChI=1S/C11H12N2O2/c1-2-13-10(14)9(12-11(13)15)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H,12,15)

FORMULA


C11H12N2O2

Responsive image

Common name


Ethotoin

IUPAC name


3-ethyl-5-phenylimidazolidine-2,4-dione

Molecular weight


204.225

clogP


1.131

clogS


-2.203

HBond Acceptor


2

HBond Donor


1

Total Polar
Surface Area


49.41

Number of Rings


2

Rotatable Bond


2

Drug ID Common name Structure CAS SMILE Frequency
FDBF00005 benzene Responsive image c1ccccc1 0.2824
FDBF00535 (5R)-5-phenylimidazolidine-2,4-dione Responsive image c1(ccccc1)C2C(=O)NC(=O)N2 0.0010
FDBF00537 imidazole-2,4-dione Responsive image O=C1NC(=O)N=C1 0.0021
FDBF01741 3-ethylimidazole-2,4-dione Responsive image C(C)N1C(=O)C=NC1=O 0.0003
4 , 1