Responsive image

Common name


Methimazole

IUPAC name


1-methyl-2,3-dihydro-1H-imidazole-2-thione

SMILES


CN1C=CNC1=S

Compound class


Antithyroid Agents; Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins; Thyroid Therapy; Sulfur-Containing Imidazole Derivatives; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2A6 Inhibitors; CYP2A6 Inhibitors (strong); CYP2A6 Inhibitors (moderate); CYP2A6 Inducers; CYP2A6 Inducers (strong); CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors;

Therapeutic area


For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Common name


Methimazole

IUPAC name


1-methyl-2,3-dihydro-1H-imidazole-2-thione

SMILES


CN1C=CNC1=S

INCHI


InChI=1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)

FORMULA


C4H6N2S

Responsive image

Common name


Methimazole

IUPAC name


1-methyl-2,3-dihydro-1H-imidazole-2-thione

Molecular weight


114.169

clogP


2.061

clogS


-0.548

HBond Acceptor


1

HBond Donor


1

Total Polar
Surface Area


52.81

Number of Rings


1

Rotatable Bond


0

Drug ID Common name Structure CAS SMILE Frequency
FDBF01746 3-methyl-1H-imidazole-2-thione Responsive image S=c1n(cc[nH]1)C 0.0003
1 , 1