IUPAC name
N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
SMILES
CCN(CC1=CC=NC=C1)C(=O)C(CO)C1=CC=CC=C1
Compound class
Muscarinic Antagonists; Mydriatics; Diagnostic Agents; Ophthalmologicals; Sensory Organs; Anticholinergics; Mydriatics and Cycloplegics;
Therapeutic area
Indicated to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) in diagnostic procedures, such as measurement of refractive errors and examination of the fundus of the eye.
Common name
Tropicamide
IUPAC name
N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
SMILES
CCN(CC1=CC=NC=C1)C(=O)C(CO)C1=CC=CC=C1
INCHI
InChI=1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
FORMULA
C17H20N2O2
Common name
Tropicamide
IUPAC name
N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
Molecular weight
284.353
clogP
2.675
clogS
-3.536
HBond Acceptor
3
HBond Donor
1
Total Polar Surface Area
53.43
Number of Rings
2
Rotatable Bond
7
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00014 | pyridine |
|
c1cccnc1 | 0.0333 |
| FDBF00015 | acetamide |
|
NC(=O)C | 0.0460 |
| FDBF00023 | toluene |
|
c1(ccccc1)C | 0.1268 |
| FDBF00253 | 2-phenylethanol |
|
c1(ccccc1)CCO | 0.0038 |
| FDBF00586 | 2-phenylacetamide |
|
O=C(N)Cc1ccccc1 | 0.0058 |
| FDBF01782 | 3-hydroxy-N-methyl-propanamide |
|
C(O)CC(=O)NC | 0.0007 |
| FDBF01843 | N-ethyl-N-methyl-formamide |
|
O=CN(C)CC | 0.0010 |
| FDBF01845 | N-ethyl-N-methyl-acetamide |
|
O=C(N(C)CC)C | 0.0003 |
| FDBF01850 | (2S)-3-hydroxy-N-methyl-2-phenyl-propanamide |
|
O=C(NC)C(c1ccccc1)CO | 0.0003 |
