IUPAC name
3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide
SMILES
NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1
Compound class
Anti-Ulcer Agents; Alimentary Tract and Metabolism; Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord); Drugs for Acid Related Disorders; Cytochrome P-450 CYP2C19 Inducers; H2 Antagonists;
Therapeutic area
For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).
Common name
Famotidine
IUPAC name
3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide
SMILES
NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1
INCHI
InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
FORMULA
C8H15N7O2S3
Common name
Famotidine
IUPAC name
3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide
Molecular weight
337.445
clogP
-0.468
clogS
-1.113
HBond Acceptor
4
HBond Donor
8
Total Polar
Surface Area
229.37
Number of Rings
1
Rotatable Bond
7
