IUPAC name
methyl(3-{tetracyclo[6.6.2.0²,
SMILES
CNCCCC12CCC(C3=CC=CC=C13)C1=CC=CC=C21
Compound class
Antidepressive Agents, Second-Generation; Adrenergic Uptake Inhibitors; Antidepressive Agents; Nervous System; Antidepressants; Psychoanaleptics; Non-Selective Monoamine Reuptake Inhibitors; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong);
Therapeutic area
For treatment of depression, including the depressed phase of bipolar depression, psychotic depression, and involutional melancholia, and may also be helpful in treating certain patients suffering severe depressive neurosis.
Common name
Maprotiline
IUPAC name
methyl(3-{tetracyclo[6.6.2.0²,
SMILES
CNCCCC12CCC(C3=CC=CC=C13)C1=CC=CC=C21
INCHI
InChI=1S/C20H23N/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20/h2-5,7-10,15,21H,6,11-14H2,1H3
FORMULA
C20H23N
Common name
Maprotiline
IUPAC name
methyl(3-{tetracyclo[6.6.2.0²,
Molecular weight
277.403
clogP
5.057
clogS
-6.215
HBond Acceptor
0
HBond Donor
1
Total Polar Surface Area
12.03
Number of Rings
4
Rotatable Bond
4
