IUPAC name
1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
SMILES
CC(C)NCC(O)COC1=CC=CC2=C1C=CN2
Compound class
Antihypertensive Agents; Vasodilator Agents; Serotonin Antagonists; Adrenergic beta-Antagonists; Cardiovascular System; Beta Blocking Agents; Beta Blocking Agents, Non-Selective; CYP2D6 Inducers; CYP2D6 Inducers (strong);
Therapeutic area
For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.
Common name
Pindolol
IUPAC name
1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
SMILES
CC(C)NCC(O)COC1=CC=CC2=C1C=CN2
INCHI
InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3
FORMULA
C14H20N2O2
Common name
Pindolol
IUPAC name
1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
Molecular weight
248.321
clogP
2.534
clogS
-3.430
HBond Acceptor
2
HBond Donor
3
Total Polar Surface Area
57.28
Number of Rings
2
Rotatable Bond
6
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00010 | indole |
|
[nH]1ccc2c1cccc2 | 0.0086 |
| FDBF00042 | propan-2-ol |
|
CC(O)C | 0.0278 |
| FDBF00208 | propan-2-amine |
|
CC(N)C | 0.0210 |
| FDBF00212 | N-methylpropan-2-amine |
|
CNC(C)C | 0.0158 |
| FDBF01290 | (2R)-1-(isopropylamino)propan-2-ol |
|
CC(CNC(C)C)O | 0.0010 |
| FDBF02170 | 4-methoxy-1H-indole |
|
COc1c2c([nH]cc2)ccc1 | 0.0003 |
16 ,
2
