IUPAC name
N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide
SMILES
CCN(C(C)=O)C1=CC=CC(=C1)C1=CC=NC2=C(C=NN12)C#N
Compound class
Hypnotics and Sedatives; Nervous System; Psycholeptics; Benzodiazepine Related Drugs; CYP3A4 Inhibitors;
Therapeutic area
For the treatment of short-term treatment of insomnia in adults.
Common name
Zaleplon
IUPAC name
N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide
SMILES
CCN(C(C)=O)C1=CC=CC(=C1)C1=CC=NC2=C(C=NN12)C#N
INCHI
InChI=1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3
FORMULA
C17H15N5O
Common name
Zaleplon
IUPAC name
N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide
Molecular weight
305.334
clogP
1.792
clogS
-3.708
HBond Acceptor
4
HBond Donor
0
Total Polar Surface Area
74.29
Number of Rings
3
Rotatable Bond
5
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00015 | acetamide |
|
NC(=O)C | 0.0460 |
| FDBF00228 | N-ethylacetamide |
|
C(=O)(NCC)C | 0.0089 |
| FDBF01320 | N-phenylacetamide |
|
c1(ccccc1)NC(=O)C | 0.0027 |
| FDBF02174 | 7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonitrile |
|
n12ncc(c1nccc2c3ccccc3)C#N | 0.0003 |
| FDBF02175 | N-ethyl-N-phenyl-acetamide |
|
O=C(N(CC)c1ccccc1)C | 0.0003 |
| FDBF02176 | pyrazolo[1,5-a]pyrimidine-3-carbonitrile |
|
n12ncc(c1nccc2)C#N | 0.0003 |
7 ,
1
