IUPAC name
3-(diphenyl-1,3-oxazol-2-yl)propanoic acid
SMILES
OC(=O)CCC1=NC(=C(O1)C1=CC=CC=C1)C1=CC=CC=C1
Compound class
Anti-Inflammatory Agents, Non-Steroidal; Musculo-Skeletal System; Antiinflammatory and Antirheumatic Products, Non-Steroids; Antiinflammatory and Antirheumatic Products; Propionic Acid Derivatives; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C9 Inducers;
Therapeutic area
Used to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis.
Common name
Oxaprozin
IUPAC name
3-(diphenyl-1,3-oxazol-2-yl)propanoic acid
SMILES
OC(=O)CCC1=NC(=C(O1)C1=CC=CC=C1)C1=CC=CC=C1
INCHI
InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)
FORMULA
C18H15NO3
Common name
Oxaprozin
IUPAC name
3-(diphenyl-1,3-oxazol-2-yl)propanoic acid
Molecular weight
293.317
clogP
4.075
clogS
-4.934
HBond Acceptor
4
HBond Donor
1
Total Polar Surface Area
63.33
Number of Rings
3
Rotatable Bond
5
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00004 | acetic acid |
|
CC(=O)O | 0.0687 |
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00047 | propionic acid |
|
CCC(=O)O | 0.0395 |
| FDBF02230 | 5-phenyloxazole |
|
c1(ccccc1)c2ocnc2 | 0.0007 |
| FDBF02231 | 4-phenyloxazole |
|
c1(ccccc1)c2cocn2 | 0.0007 |
| FDBF02232 | 2-methyloxazole |
|
Cc1occn1 | 0.0003 |
| FDBF02233 | 2-methyl-5-phenyl-oxazole |
|
c1(ccccc1)c2oc(nc2)C | 0.0003 |
| FDBF02234 | 2-methyl-4-phenyl-oxazole |
|
c1(ccccc1)c2coc(n2)C | 0.0003 |
| FDBF02235 | oxazole |
|
o1ccnc1 | 0.0007 |
