IUPAC name
2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one
SMILES
NC1=NC2=C(N=CN2COC(CO)CO)C(=O)N1
Compound class
Antiviral Agents; Ophthalmologicals; Sensory Organs; Antiinfectives for Systemic Use; Direct Acting Antivirals; Antivirals for Systemic Use; Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors; Antiinfectives;
Therapeutic area
For induction and maintenance in the treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). Also used in the treatment of severe cytomegalovirus (CMV) disease, including CMV pneumonia, CMV gastrointestinal disease, and disseminated CMV infections, in immunocompromised patients.
Common name
Ganciclovir
IUPAC name
2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one
SMILES
NC1=NC2=C(N=CN2COC(CO)CO)C(=O)N1
INCHI
InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
FORMULA
C9H13N5O4
Common name
Ganciclovir
IUPAC name
2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one
Molecular weight
255.231
clogP
-1.001
clogS
-0.596
HBond Acceptor
6
HBond Donor
5
Total Polar Surface Area
139.28
Number of Rings
2
Rotatable Bond
5
