Responsive image

Common name


Fenofibrate

IUPAC name


propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

SMILES


CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1

Compound class


Anticholesteremic Agents; Hypolipidemic Agents; Lipid Modifying Agents, Plain; Lipid Modifying Agents; Cardiovascular System; Fibrates; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP3A4 Inhibitors;

Therapeutic area


For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb).

Common name


Fenofibrate

IUPAC name


propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

SMILES


CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1

INCHI


InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3

FORMULA


C20H21ClO4

Responsive image

Common name


Fenofibrate

IUPAC name


propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

Molecular weight


360.831

clogP


4.949

clogS


-5.297

HBond Acceptor


4

HBond Donor


0

Total Polar
Surface Area


52.6

Number of Rings


2

Rotatable Bond


7

Drug ID Common name Structure CAS SMILE Frequency
FDBF00005 benzene Responsive image c1ccccc1 0.2824
FDBF00007 propane Responsive image C(C)C 0.2412
FDBF00016 chlorobenzene Responsive image c1ccc(cc1)Cl 0.0718
FDBF01007 benzaldehyde Responsive image c1(ccccc1)C=O 0.0086
FDBF01049 4-hydroxybenzaldehyde Responsive image c1(ccc(cc1)C=O)O 0.0014
FDBF02321 isopropyl 2-methylpropanoate Responsive image C(C)(C)C(=O)OC(C)C 0.0003
FDBF02322 4-chlorobenzaldehyde Responsive image O=Cc1ccc(cc1)Cl 0.0007
FDBF02323 isopropoxybenzene Responsive image c1(ccccc1)OC(C)C 0.0007
FDBF02324 isopropyl 2-hydroxy-2-methyl-propanoate Responsive image C(C)(C)(C(=O)OC(C)C)O 0.0003
FDBF02325 4-isopropoxybenzaldehyde Responsive image c1(ccc(cc1)C=O)OC(C)C 0.0003
13 , 2