
IUPAC name
propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
SMILES
CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1
Compound class
Anticholesteremic Agents; Hypolipidemic Agents; Lipid Modifying Agents, Plain; Lipid Modifying Agents; Cardiovascular System; Fibrates; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP3A4 Inhibitors;
Therapeutic area
For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb).
Common name
Fenofibrate
IUPAC name
propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
SMILES
CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1
INCHI
InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
FORMULA
C20H21ClO4

Common name
Fenofibrate
IUPAC name
propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
Molecular weight
360.831
clogP
4.949
clogS
-5.297
HBond Acceptor
4
HBond Donor
0
Total Polar Surface Area
52.6
Number of Rings
2
Rotatable Bond
7
Drug ID | Common name | Structure CAS | SMILE | Frequency |
---|---|---|---|---|
FDBF00005 | benzene |
![]() |
c1ccccc1 | 0.2824 |
FDBF00007 | propane |
![]() |
C(C)C | 0.2412 |
FDBF00016 | chlorobenzene |
![]() |
c1ccc(cc1)Cl | 0.0718 |
FDBF01007 | benzaldehyde |
![]() |
c1(ccccc1)C=O | 0.0086 |
FDBF01049 | 4-hydroxybenzaldehyde |
![]() |
c1(ccc(cc1)C=O)O | 0.0014 |
FDBF02321 | isopropyl 2-methylpropanoate |
![]() |
C(C)(C)C(=O)OC(C)C | 0.0003 |
FDBF02322 | 4-chlorobenzaldehyde |
![]() |
O=Cc1ccc(cc1)Cl | 0.0007 |
FDBF02323 | isopropoxybenzene |
![]() |
c1(ccccc1)OC(C)C | 0.0007 |
FDBF02324 | isopropyl 2-hydroxy-2-methyl-propanoate |
![]() |
C(C)(C)(C(=O)OC(C)C)O | 0.0003 |
FDBF02325 | 4-isopropoxybenzaldehyde |
![]() |
c1(ccc(cc1)C=O)OC(C)C | 0.0003 |