IUPAC name
dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine
SMILES
CC(CN1C2=CC=CC=C2SC2=CC=CC=C12)N(C)C
Compound class
Anti-Allergic Agents; Antipruritics; Histamine H1 Antagonists; Antidotes; Respiratory System; Dermatologicals; Antipruritics, Incl. Antihistamines, Anesthetics, Etc.; Antihistamines for Topical Use; Antihistamines for Systemic Use; Phenothiazine Derivatives; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong);
Therapeutic area
For the treatment of allergic disorders, and nausea/vomiting.
Common name
Promethazine
IUPAC name
dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine
SMILES
CC(CN1C2=CC=CC=C2SC2=CC=CC=C12)N(C)C
INCHI
InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
FORMULA
C17H20N2S
Common name
Promethazine
IUPAC name
dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine
Molecular weight
284.419
clogP
3.139
clogS
-4.090
HBond Acceptor
2
HBond Donor
0
Total Polar Surface Area
31.78
Number of Rings
3
Rotatable Bond
3
