
IUPAC name
{2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine
SMILES
CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=CC=CC=C2O1
Compound class
Enzyme Inhibitors; Anti-Arrhythmia Agents; Potassium Channel Blockers; Vasodilator Agents; Sodium Channel Blockers; Cardiovascular System; Antiarrhythmics, Class III; Antiarrhythmics, Class I and Iii; Cardiac Therapy; Antiarrythmics, Class I and Iii; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2A6 Inhibitors; CYP2A6 Inhibitors (strong); CYP2A6 Inhibitors (moderate); CYP2A6 Inducers; CYP2A6 Inducers (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; Combined Inhibitors of CYP3A4 and P-glycoprotein;
Therapeutic area
Intravenously, for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy. Orally, for the treatment of life-threatening recurrent ventricular arrhythmias such as recurrent ventricular fibrillation and recurrent hemodynamically unstable ventricular tachycardia.
Common name
Amiodarone
IUPAC name
{2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine
SMILES
CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=CC=CC=C2O1
INCHI
InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3
FORMULA
C25H29I2NO3

Common name
Amiodarone
IUPAC name
{2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine
Molecular weight
645.312
clogP
8.240
clogS
-9.452
HBond Acceptor
4
HBond Donor
0
Total Polar Surface Area
42.68
Number of Rings
3
Rotatable Bond
11
Drug ID | Common name | Structure CAS | SMILE | Frequency |
---|---|---|---|---|
FDBF00007 | propane |
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C(C)C | 0.2412 |
FDBF00040 | ethanamine |
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CCN | 0.0677 |
FDBF00041 | ethanol |
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CCO | 0.1474 |
FDBF00068 | N-methylethanamine |
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N(CC)C | 0.0429 |
FDBF00294 | N-ethyl-N-methyl-ethanamine |
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C(C)N(CC)C | 0.0134 |
FDBF00729 | 2-(ethylamino)ethanol |
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N(CCO)CC | 0.0065 |
FDBF02535 | 2-methylbenzofuran |
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Cc1oc2c(c1)cccc2 | 0.0007 |
FDBF02536 | benzofuran-3-carbaldehyde |
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o1cc(c2c1cccc2)C=O | 0.0007 |
FDBF02537 | benzofuran |
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o1ccc2c1cccc2 | 0.0010 |