IUPAC name
1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
SMILES
ClC1=CC(Cl)=C(C=C1)C(CN1C=CN=C1)OCC1=CSC2=C1C=CC=C2Cl
Compound class
Antifungal Agents; Genito Urinary System and Sex Hormones; Dermatologicals; Gynecological Antiinfectives and Antiseptics; Imidazole and Triazole Derivatives; Antifungals for Topical Use; Antifungals for Dermatological Use; Imidazole Derivatives;
Therapeutic area
For the topical treatment of interdigital tinea pedis in immunocompetent patients 12 years of age and older, caused by .
Common name
Sertaconazole
IUPAC name
1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
SMILES
ClC1=CC(Cl)=C(C=C1)C(CN1C=CN=C1)OCC1=CSC2=C1C=CC=C2Cl
INCHI
InChI=1S/C20H15Cl3N2OS/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22/h1-8,11-12,19H,9-10H2
FORMULA
C20H15Cl3N2OS
Common name
Sertaconazole
IUPAC name
1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
Molecular weight
437.770
clogP
6.902
clogS
-7.209
HBond Acceptor
2
HBond Donor
0
Total Polar Surface Area
55.29
Number of Rings
4
Rotatable Bond
6
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00011 | imidazole |
|
[nH]1ccnc1 | 0.0175 |
| FDBF00041 | ethanol |
|
CCO | 0.1474 |
| FDBF00168 | methoxyethane |
|
CCOC | 0.0254 |
| FDBF00490 | 1-methylimidazole |
|
n1(ccnc1)C | 0.0058 |
| FDBF00653 | 1-ethylimidazole |
|
C(C)n1ccnc1 | 0.0031 |
| FDBF02255 | (2,4-dichlorophenyl)methanol |
|
C(O)c1c(cc(cc1)Cl)Cl | 0.0021 |
| FDBF02256 | 1-[2-(2,4-dichlorophenyl)ethyl]imidazole |
|
C(Cn1ccnc1)c2c(cc(cc2)Cl)Cl | 0.0021 |
| FDBF02257 | 2-imidazol-1-ylethanol |
|
C(Cn1ccnc1)O | 0.0017 |
| FDBF02258 | 1-(2-methoxyethyl)imidazole |
|
COCCn1ccnc1 | 0.0017 |
| FDBF02259 | (1R)-1-(2,4-dichlorophenyl)-2-imidazol-1-yl-ethanol |
|
C(Cn1ccnc1)(O)c2c(cc(cc2)Cl)Cl | 0.0017 |
