IUPAC name
(10S,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0³,
SMILES
[H][C@]12COC(=O)[C@]1([H])[C@@H](C1=CC(OC)=C(OC)C(OC)=C1)C1=CC3=C(OCO3)C=C1[C@@H]2O
Compound class
Antiviral Agents; Antineoplastic Agents, Phytogenic; Tubulin Modulators; Keratolytic Agents; Antimitotic Agents; Dermatologicals; Cytochrome P-450 CYP2C19 Inducers; CYP3A4 Inhibitors;
Therapeutic area
For treatment of external genital warts (.
Common name
Podofilox
IUPAC name
(10S,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0³,
SMILES
[H][C@]12COC(=O)[C@]1([H])[C@@H](C1=CC(OC)=C(OC)C(OC)=C1)C1=CC3=C(OCO3)C=C1[C@@H]2O
INCHI
InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18-,19-,20-/m0/s1
FORMULA
C22H22O8
Common name
Podofilox
IUPAC name
(10S,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0³,
Molecular weight
414.405
clogP
2.899
clogS
-4.147
HBond Acceptor
8
HBond Donor
1
Total Polar Surface Area
92.68
Number of Rings
5
Rotatable Bond
4
