IUPAC name
(4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1λ
SMILES
CCN[C@H]1CN(CCCOC)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
Compound class
Carbonic Anhydrase Inhibitors; Anti-glaucoma Agents; Ophthalmics; Ophthalmologicals; Sensory Organs; Antiglaucoma Preparations and Miotics; CYP3A4 Inhibitors;
Therapeutic area
For the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Common name
Brinzolamide
IUPAC name
(4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1λ
SMILES
CCN[C@H]1CN(CCCOC)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
INCHI
InChI=1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1
FORMULA
C12H21N3O5S3
Common name
Brinzolamide
IUPAC name
(4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1λ
Molecular weight
383.507
clogP
0.082
clogS
-2.785
HBond Acceptor
5
HBond Donor
3
Total Polar Surface Area
147.04
Number of Rings
2
Rotatable Bond
7
