IUPAC name
1,1-diphenyl-4-(piperidin-1-yl)butan-1-ol
SMILES
OC(CCCN1CCCCC1)(C1=CC=CC=C1)C1=CC=CC=C1
Compound class
Antiemetics;
Therapeutic area
For use in the prevention and symptomatic treatment of peripheral (labyrinthine) vertigo and associated nausea and vomiting that occur in such conditions as Meniere's disease and surgery of the middle and inner ear. Also for the control of nausea and vomiting associated with postoperative states, malignant neoplasms, labyrinthine disturbances, antineoplastic agent therapy, radiation sickness, and infectious diseases.
Common name
Diphenidol
IUPAC name
1,1-diphenyl-4-(piperidin-1-yl)butan-1-ol
SMILES
OC(CCCN1CCCCC1)(C1=CC=CC=C1)C1=CC=CC=C1
INCHI
InChI=1S/C21H27NO/c23-21(19-11-4-1-5-12-19,20-13-6-2-7-14-20)15-10-18-22-16-8-3-9-17-22/h1-2,4-7,11-14,23H,3,8-10,15-18H2
FORMULA
C21H27NO
Common name
Diphenidol
IUPAC name
1,1-diphenyl-4-(piperidin-1-yl)butan-1-ol
Molecular weight
309.445
clogP
4.511
clogS
-4.797
HBond Acceptor
2
HBond Donor
1
Total Polar Surface Area
23.47
Number of Rings
3
Rotatable Bond
6
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00018 | propan-1-ol |
|
C(O)CC | 0.0330 |
| FDBF00041 | ethanol |
|
CCO | 0.1474 |
| FDBF00309 | (1R)-1-phenylethanol |
|
CC(O)c1ccccc1 | 0.0034 |
| FDBF00635 | (1R)-1-phenylpropan-1-ol |
|
C(C(O)c1ccccc1)C | 0.0017 |
| FDBF00670 | piperidine |
|
N1CCCCC1 | 0.0199 |
| FDBF00671 | 1-ethylpiperidine |
|
N1(CCCCC1)CC | 0.0106 |
| FDBF00695 | (1R)-1-phenylbutan-1-ol |
|
c1(ccccc1)C(O)CCC | 0.0007 |
| FDBF01063 | (1S)-1-phenylethanol |
|
c1(ccccc1)C(C)O | 0.0031 |
| FDBF02155 | (1S)-1-phenylbutan-1-ol |
|
C(CC(O)c1ccccc1)C | 0.0007 |
