IUPAC name
6-chloro-2-methyl-1,1-dioxo-3-{[(2,2,2-trifluoroethyl)sulfanyl]methyl}-3,4-dihydro-2H-1λ
SMILES
CN1C(CSCC(F)(F)F)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
Compound class
Antihypertensive Agents; Diuretics; Sodium Chloride Symporter Inhibitors; Cardiovascular System; Thiazides, Plain; Low-Ceiling Diuretics, Thiazides;
Therapeutic area
Polythiazide is a thiazide diuretic used to decrease edema and decrease blood pressure.
Common name
Polythiazide
IUPAC name
6-chloro-2-methyl-1,1-dioxo-3-{[(2,2,2-trifluoroethyl)sulfanyl]methyl}-3,4-dihydro-2H-1λ
SMILES
CN1C(CSCC(F)(F)F)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
INCHI
InChI=1S/C11H13ClF3N3O4S3/c1-18-10(4-23-5-11(13,14)15)17-7-2-6(12)8(24(16,19)20)3-9(7)25(18,21)22/h2-3,10,17H,4-5H2,1H3,(H2,16,19,20)
FORMULA
C11H13ClF3N3O4S3
Common name
Polythiazide
IUPAC name
6-chloro-2-methyl-1,1-dioxo-3-{[(2,2,2-trifluoroethyl)sulfanyl]methyl}-3,4-dihydro-2H-1λ
Molecular weight
439.882
clogP
0.392
clogS
-3.711
HBond Acceptor
4
HBond Donor
3
Total Polar Surface Area
134.87
Number of Rings
2
Rotatable Bond
5
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00052 | methylsulfanylmethane |
|
S(C)C | 0.0072 |
| FDBF00177 | fluoroform |
|
FC(F)F | 0.0704 |
| FDBF00473 | 6-chloro-2-methyl-3,4-dihydrobenzo[e][1,2,4]thiadiazine 1,1-dioxide |
|
Clc1cc2c(cc1)S(=O)(=O)N(CN2)C | 0.0007 |
| FDBF00974 | 1,1,1-trifluoroethane |
|
CC(F)(F)F | 0.0072 |
| FDBF02937 | (3S)-6-chloro-2,3-dimethyl-3,4-dihydrobenzo[e][1,2,4]thiadiazine 1,1-dioxide |
|
CC1Nc2cc(ccc2S(=O)(=O)N1C)Cl | 0.0003 |
| FDBF02938 | 2,2,2-trifluoroethanethiol |
|
C(S)C(F)(F)F | 0.0003 |
| FDBF02939 | 1,1,1-trifluoro-2-methylsulfanyl-ethane |
|
CSCC(F)(F)F | 0.0003 |
