IUPAC name
7-chloro-1-(cyclopropylmethyl)-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
SMILES
ClC1=CC2=C(C=C1)N(CC1CC1)C(=O)CN=C2C1=CC=CC=C1
Compound class
Anti-Anxiety Agents; GABA Modulators; Nervous System; Benzodiazepine Derivatives; Anxiolytics; Psycholeptics; CYP3A4 Inhibitors;
Therapeutic area
For the treatment of anxiety disorders.
Common name
Prazepam
IUPAC name
7-chloro-1-(cyclopropylmethyl)-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
SMILES
ClC1=CC2=C(C=C1)N(CC1CC1)C(=O)CN=C2C1=CC=CC=C1
INCHI
InChI=1S/C19H17ClN2O/c20-15-8-9-17-16(10-15)19(14-4-2-1-3-5-14)21-11-18(23)22(17)12-13-6-7-13/h1-5,8-10,13H,6-7,11-12H2
FORMULA
C19H17ClN2O
Common name
Prazepam
IUPAC name
7-chloro-1-(cyclopropylmethyl)-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Molecular weight
324.804
clogP
4.940
clogS
-5.388
HBond Acceptor
2
HBond Donor
0
Total Polar
Surface Area
32.67
Number of Rings
4
Rotatable Bond
3
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00250 | methylcyclopropane |
|
CC1CC1 | 0.0038 |
| FDBF00259 | cyclopropane |
|
C1CC1 | 0.0175 |
| FDBF01604 | 7-chloro-1-methyl-3H-1,4-benzodiazepin-2-one |
|
Clc1cc2c(cc1)N(C(=O)CN=C2)C | 0.0021 |
| FDBF01607 | 7-chloro-1,3-dihydro-1,4-benzodiazepin-2-one |
|
Clc1cc2c(cc1)NC(=O)CN=C2 | 0.0017 |
5 ,
1
