IUPAC name
3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol
SMILES
CC[C@H]([C@@H](C)CN(C)C)C1=CC(O)=CC=C1
Compound class
Analgesics; Nervous System; Opioids; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong);
Therapeutic area
The immediate-release formulation of tapentadol is indicated for the relief of moderate to severe acute pain. The long-acting formulation serves as a continuous, around-the-clock analgesic that is indicated for the relief of moderate to severe chronic pain or neuropathic pain associated with diabetic peripheral neuropathy.
Common name
Tapentadol
IUPAC name
3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol
SMILES
CC[C@H]([C@@H](C)CN(C)C)C1=CC(O)=CC=C1
INCHI
InChI=1S/C14H23NO/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12/h6-9,11,14,16H,5,10H2,1-4H3/t11-,14+/m0/s1
FORMULA
C14H23NO
Common name
Tapentadol
IUPAC name
3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol
Molecular weight
221.339
clogP
2.776
clogS
-3.016
HBond Acceptor
2
HBond Donor
1
Total Polar Surface Area
23.47
Number of Rings
1
Rotatable Bond
5
