IUPAC name
(2R)-N-benzyl-2-acetamido-3-methoxypropanamide
SMILES
COC[C@@H](NC(C)=O)C(=O)NCC1=CC=CC=C1
Compound class
Anticonvulsants; Nervous System; Antiepileptics;
Therapeutic area
Lacosamide is indicated for adjunctive therapy for partial onset seizures in patients with epilepsy over 17 years old. Injection is indicated for short term use when oral therapy is not feasible.
Common name
Lacosamide
IUPAC name
(2R)-N-benzyl-2-acetamido-3-methoxypropanamide
SMILES
COC[C@@H](NC(C)=O)C(=O)NCC1=CC=CC=C1
INCHI
InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
FORMULA
C13H18N2O3
Common name
Lacosamide
IUPAC name
(2R)-N-benzyl-2-acetamido-3-methoxypropanamide
Molecular weight
250.294
clogP
1.385
clogS
-3.020
HBond Acceptor
3
HBond Donor
2
Total Polar Surface Area
67.43
Number of Rings
1
Rotatable Bond
6
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00003 | formamide |
|
C(=O)N | 0.1240 |
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00027 | N-methylacetamide |
|
N(C(=O)C)C | 0.0175 |
| FDBF00031 | N-methylpropanamide |
|
N(C(=O)CC)C | 0.0069 |
| FDBF00168 | methoxyethane |
|
CCOC | 0.0254 |
| FDBF00182 | N-benzylformamide |
|
c1(ccccc1)CNC=O | 0.0038 |
| FDBF00186 | N-benzylpropanamide |
|
CCC(=O)NCc1ccccc1 | 0.0007 |
| FDBF00228 | N-ethylacetamide |
|
C(=O)(NCC)C | 0.0089 |
| FDBF01215 | N-(2-methoxyethyl)acetamide |
|
CC(=O)NCCOC | 0.0010 |
| FDBF03398 | 3-methoxypropanamide |
|
C(CC(=O)N)OC | 0.0003 |
18 ,
2
