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Common name


Eflornithine

IUPAC name


2,5-diamino-2-(difluoromethyl)pentanoic acid

SMILES


NCCCC(N)(C(F)F)C(O)=O

Compound class


Antineoplastic Agents; Enzyme Inhibitors; Antiprotozoal Agents; Trypanocidal Agents; Dermatologicals; Antiparasitic Products, Insecticides and Repellents; Agents Against Leishmaniasis and Trypanosomiasis; Ornithine Decarboxylase Inhibitors;

Therapeutic area


Eflornithine is indicated in the treatment of facial hirsutism (excessive hair growth).

Common name


Eflornithine

IUPAC name


2,5-diamino-2-(difluoromethyl)pentanoic acid

SMILES


NCCCC(N)(C(F)F)C(O)=O

INCHI


InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12)

FORMULA


C6H12F2N2O2

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Common name


Eflornithine

IUPAC name


2,5-diamino-2-(difluoromethyl)pentanoic acid

Molecular weight


182.168

clogP


-0.249

clogS


-0.406

HBond Acceptor


2

HBond Donor


5

Total Polar
Surface Area


89.34

Number of Rings


0

Rotatable Bond


5

Drug ID Common name Structure CAS SMILE Frequency
FDBF00025 propan-1-amine Responsive image CCCN 0.0292
FDBF00040 ethanamine Responsive image CCN 0.0677
FDBF00370 difluoromethane Responsive image FCF 0.0151
3 , 1