IUPAC name
2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
SMILES
OC(=O)COCCN1CCN(CC1)[C@H](C1=CC=CC=C1)C1=CC=C(Cl)C=C1
Compound class
Respiratory System; Antihistamines for Systemic Use; Piperazine Derivatives; CYP3A4 Inhibitors;
Therapeutic area
Levocetirizine is indicated for the relief of symptoms associated with allergic rhinitis (seasonal and perennial) in adults and children 6 years of age and older.
Common name
Levocetirizine
IUPAC name
2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
SMILES
OC(=O)COCCN1CCN(CC1)[C@H](C1=CC=CC=C1)C1=CC=C(Cl)C=C1
INCHI
InChI=1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)/t21-/m1/s1
FORMULA
C21H25ClN2O3
Common name
Levocetirizine
IUPAC name
2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
Molecular weight
388.888
clogP
3.353
clogS
-4.258
HBond Acceptor
5
HBond Donor
1
Total Polar Surface Area
53.01
Number of Rings
3
Rotatable Bond
8
