IUPAC name
N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
SMILES
COC1=CC=C(CN(CCN(C)C)C2=NC=CC=C2)C=C1
Compound class
Anti-Allergic Agents; Histamine H1 Antagonists; Histamine Antagonists; Respiratory System; Dermatologicals; Antipruritics, Incl. Antihistamines, Anesthetics, Etc.; Antihistamines for Topical Use; Antihistamines for Systemic Use; Substituted Ethylene Diamines; Sleep Aids, Pharmaceutical; CYP2D6 Inducers; CYP2D6 Inducers (strong);
Therapeutic area
Mepyramine is a first generation antihistamine used in treating allergies, ymptomatic relief of hypersensitivity reaction, and in pruritic skin disorders.
Common name
Mepyramine
IUPAC name
N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
SMILES
COC1=CC=C(CN(CCN(C)C)C2=NC=CC=C2)C=C1
INCHI
InChI=1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15/h4-11H,12-14H2,1-3H3
FORMULA
C17H23N3O
Common name
Mepyramine
IUPAC name
N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
Molecular weight
285.384
clogP
2.357
clogS
-4.116
HBond Acceptor
4
HBond Donor
0
Total Polar Surface Area
28.6
Number of Rings
2
Rotatable Bond
7
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00014 | pyridine |
|
c1cccnc1 | 0.0333 |
| FDBF00023 | toluene |
|
c1(ccccc1)C | 0.1268 |
| FDBF00068 | N-methylethanamine |
|
N(CC)C | 0.0429 |
| FDBF00211 | anisole |
|
COc1ccccc1 | 0.0423 |
| FDBF00909 | N-ethyl-N-methyl-pyridin-2-amine |
|
n1c(cccc1)N(C)CC | 0.0014 |
| FDBF01793 | pyridin-2-amine |
|
Nc1ncccc1 | 0.0031 |
| FDBF03530 | (4-methoxyphenyl)methanamine |
|
O(C)c1ccc(cc1)CN | 0.0003 |
| FDBF03531 | 1-(4-methoxyphenyl)-N-methyl-methanamine |
|
O(C)c1ccc(cc1)CNC | 0.0003 |
