IUPAC name
2-(2-amino-3-benzoylphenyl)acetamide
SMILES
NC(=O)CC1=CC=CC(C(=O)C2=CC=CC=C2)=C1N
Compound class
Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Prodrugs; Ophthalmologicals; Sensory Organs;
Therapeutic area
For the treatment of pain and inflammation associated with cataract surgery.
Common name
Nepafenac
IUPAC name
2-(2-amino-3-benzoylphenyl)acetamide
SMILES
NC(=O)CC1=CC=CC(C(=O)C2=CC=CC=C2)=C1N
INCHI
InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)
FORMULA
C15H14N2O2
Common name
Nepafenac
IUPAC name
2-(2-amino-3-benzoylphenyl)acetamide
Molecular weight
254.284
clogP
2.199
clogS
-3.292
HBond Acceptor
2
HBond Donor
4
Total Polar Surface Area
86.18
Number of Rings
2
Rotatable Bond
4
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00003 | formamide |
|
C(=O)N | 0.1240 |
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00015 | acetamide |
|
NC(=O)C | 0.0460 |
| FDBF00046 | aniline |
|
Nc1ccccc1 | 0.0247 |
| FDBF01007 | benzaldehyde |
|
c1(ccccc1)C=O | 0.0086 |
| FDBF01416 | 2-methylaniline |
|
Nc1ccccc1C | 0.0010 |
| FDBF02177 | 2-aminobenzaldehyde |
|
Nc1ccccc1C=O | 0.0007 |
| FDBF03599 | 2-amino-3-methyl-benzaldehyde |
|
Nc1c(cccc1C=O)C | 0.0003 |
| FDBF03600 | (2-aminophenyl)-phenyl-methanone |
|
c1(ccccc1)C(=O)c2c(cccc2)N | 0.0003 |
9 ,
1
