IUPAC name
2-[(1-hydroxy-2-sulfanylpropylidene)amino]acetic acid
SMILES
CC(S)C(O)=NCC(O)=O
Compound class
Mucolytics; Cough and Cold Preparations; Respiratory System; Genito Urinary System and Sex Hormones; Urinary Concrement Solvents; Urological Agents;
Therapeutic area
Tiopronin is indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria consisting of a urinary cystine concentration greater than 500 mg/day, and who have failed treatment with non-pharmacological measures of increased fluid intake, decreased sodium and protein intake, and urine alkalinization.
Common name
Tiopronin
IUPAC name
2-[(1-hydroxy-2-sulfanylpropylidene)amino]acetic acid
SMILES
CC(S)C(O)=NCC(O)=O
INCHI
InChI=1S/C5H9NO3S/c1-3(10)5(9)6-2-4(7)8/h3,10H,2H2,1H3,(H,6,9)(H,7,8)
FORMULA
C5H9NO3S
Common name
Tiopronin
IUPAC name
2-[(1-hydroxy-2-sulfanylpropylidene)amino]acetic acid
Molecular weight
163.195
clogP
0.121
clogS
0.286
HBond Acceptor
4
HBond Donor
3
Total Polar Surface Area
108.69
Number of Rings
0
Rotatable Bond
3
