IUPAC name
N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
SMILES
C(N(CC1=CC=CC=C1)C1=CC=CC=C1)C1=NCCN1
Compound class
Anti-Allergic Agents; Histamine H1 Antagonists; Histamine Antagonists; Respiratory System; Nasal Preparations; Antihistamines for Systemic Use; Antiallergic Agents, Excl. Corticosteroids;
Therapeutic area
Used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.
Common name
Antazoline
IUPAC name
N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
SMILES
C(N(CC1=CC=CC=C1)C1=CC=CC=C1)C1=NCCN1
INCHI
InChI=1S/C17H19N3/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16/h1-10H,11-14H2,(H,18,19)
FORMULA
C17H19N3
Common name
Antazoline
IUPAC name
N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
Molecular weight
265.353
clogP
3.503
clogS
-4.463
HBond Acceptor
2
HBond Donor
1
Total Polar Surface Area
27.63
Number of Rings
3
Rotatable Bond
5
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00011 | imidazole |
|
[nH]1ccnc1 | 0.0175 |
| FDBF00023 | toluene |
|
c1(ccccc1)C | 0.1268 |
| FDBF00046 | aniline |
|
Nc1ccccc1 | 0.0247 |
| FDBF00642 | N,N-dimethylaniline |
|
CN(C)c1ccccc1 | 0.0045 |
| FDBF00913 | phenylmethanamine |
|
NCc1ccccc1 | 0.0086 |
| FDBF01425 | N-methyl-1-phenyl-methanamine |
|
N(C)Cc1ccccc1 | 0.0045 |
| FDBF01611 | 2-methyl-1H-imidazole |
|
Cc1[nH]ccn1 | 0.0038 |
14 ,
2
