Common name
2-formamido-N-methyl-acetamide
IUPAC name
2-formamido-N-methyl-acetamide
SMILES
N(C(=O)CNC=O)C
Common name
2-formamido-N-methyl-acetamide
IUPAC name
2-formamido-N-methyl-acetamide
SMILES
N(C(=O)CNC=O)C
INCHI
InChI=1S/C4H8N2O2/c1-5-4(8)2-6-3-7/h3H,2H2,1H3,(H,5,8)(H,6,7)
FORMULA
C4H8N2O2
Common name
2-formamido-N-methyl-acetamide
IUPAC name
2-formamido-N-methyl-acetamide
Molecular weight
116.119
clogP
-0.815
clogS
-0.619
Frequency
0.0034
HBond Acceptor
2
HBond Donor
2
Total PolarSurface Area
58.2
Number of Rings
0
Rotatable Bond
2
| Drug ID | Common name | Structure CAS | Compound class | Therapeutic area |
|---|---|---|---|---|
| FDBD00006 | Felypressin |
|
Vasoconstrictor Agents; Renal Agents; | For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential. |
| FDBD00077 | Bortezomib |
|
Antineoplastic Agents; Antineoplastic and Immunomodulating Agents; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; | For treatment of multiple myeloma in patients who have not been successfully treated with at least two previous therapies. |
| FDBD00100 | Remikiren |
|
Cardiovascular System; Agents Acting on the Renin-Angiotensin System; Renin-Inhibitors; | For the treatment of hypertension and heart failure. |
| FDBD00648 | Marimastat |
|
Enzyme Inhibitors; | For the treatment of various cancers. |
| FDBD00753 | Benzylpenicilloyl Polylysine |
|
Acetamides; | For use as a adjunct in assessing the risk of administering penicillin (benzylpenicillin or penicillin G). |
| FDBD01076 | Saquinavir |
|
Protease Inhibitors; HIV Protease Inhibitors; Antiinfectives for Systemic Use; Direct Acting Antivirals; Antivirals for Systemic Use; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; Combined Inhibitors of CYP3A4 and P-glycoprotein; | For the treatment of HIV-1 with advanced immunodeficiency together with antiretroviral nucleoside analogues. |
| FDBD01114 | Carbetocin |
|
Oxytocics; Delayed-Action Preparations; Anti-tocolytic Agents; Labor Induction Agents; Pituitary and Hypothalamic Hormones and Analogues; Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins; Posterior Pituitary Lobe Hormones; Oxytocin and Analogues; | Used to control postpartum hemorrhage and bleeding after giving birth. |
| FDBD01369 | Telaprevir |
|
Protease Inhibitors; Antiinfectives for Systemic Use; Direct Acting Antivirals; Antivirals for Systemic Use; CYP3A4 Inhibitors; | Treating chronic hepatitis C virus (genotype 1) infection in patients with compensated liver (due to liver diseases like cirrhosis) that are treatment naive or have failed therapy with interferons (either null or partial responders and treatment relapsers). |
| FDBD02324 | afoxolaner |
|
Insecticide | Insecticide |
| FDBD02335 | fluralaner |
|
Insecticide | Insecticide |
10 ,
2
| FRAGNAME | PDBID | SIMILIRITY | XSCORE | SMILE | HAC |
|---|---|---|---|---|---|
| 1a7c_ligand_3_345.mol2 | 1a7c | 1 | -6.11 | CNC(=O)CNC=O | 8 |
| 1mnc_ligand_2_31.mol2 | 1mnc | 1 | -5.78 | C(=O)(NC)CNC=O | 8 |
| 4piq_ligand_3_81.mol2 | 4piq | 1 | -5.74 | CNC(=O)CNC=O | 8 |
| 3d91_ligand_3_449.mol2 | 3d91 | 1 | -5.72 | C(NC=O)C(=O)NC | 8 |
| 4wx6_ligand_3_137.mol2 | 4wx6 | 1 | -5.71 | C(=O)(NC)CNC=O | 8 |
557 ,
56
