Responsive image

Common name


N-methylpyrazine-2-carboxamide

IUPAC name


N-methylpyrazine-2-carboxamide

SMILES


C(=O)(NC)c1nccnc1

Common name


N-methylpyrazine-2-carboxamide

IUPAC name


N-methylpyrazine-2-carboxamide

SMILES


C(=O)(NC)c1nccnc1

INCHI


InChI=1S/C6H7N3O/c1-7-6(10)5-4-8-2-3-9-5/h2-4H,1H3,(H,7,10)

FORMULA


C6H7N3O

Responsive image

Common name


N-methylpyrazine-2-carboxamide

IUPAC name


N-methylpyrazine-2-carboxamide





Molecular weight


137.139

clogP


0.402

clogS


-1.556

Frequency


0.0007





HBond Acceptor


3

HBond Donor


1

Total Polar
Surface Area


54.88

Number of Rings


1

Rotatable Bond


1

Drug ID Common name Structure CAS Compound class Therapeutic area
FDBD00077 Bortezomib Responsive image Antineoplastic Agents; Antineoplastic and Immunomodulating Agents; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; For treatment of multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
FDBD01369 Telaprevir Responsive image Protease Inhibitors; Antiinfectives for Systemic Use; Direct Acting Antivirals; Antivirals for Systemic Use; CYP3A4 Inhibitors; Treating chronic hepatitis C virus (genotype 1) infection in patients with compensated liver (due to liver diseases like cirrhosis) that are treatment naive or have failed therapy with interferons (either null or partial responders and treatment relapsers).
2 , 1
FRAGNAME PDBID SIMILIRITY XSCORE SMILE HAC
100 , 11