Common name
cyclopropane
IUPAC name
cyclopropane
SMILES
C1CC1
Common name
cyclopropane
IUPAC name
cyclopropane
SMILES
C1CC1
INCHI
InChI=1S/C3H6/c1-2-3-1/h1-3H2
FORMULA
C3H6
Common name
cyclopropane
IUPAC name
cyclopropane
Molecular weight
42.080
clogP
1.949
clogS
-0.466
Frequency
0.0175
HBond Acceptor
0
HBond Donor
0
Total PolarSurface Area
0
Number of Rings
1
Rotatable Bond
0
| Drug ID | Common name | Structure CAS | Compound class | Therapeutic area |
|---|---|---|---|---|
| FDBD01658 | Olaparib |
|
Antineoplastic Agents; Antineoplastic and Immunomodulating Agents; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP3A4 Inhibitors; Poly(ADP-ribose) Polymerase Inhibitors; | Olaparib is a poly (ADP-ribose) polymerase (PARP) inhibitor indicated as monotherapy in patients with deleterious or suspected deleterious germline BRCA mutated (as detected by an FDA-approved test) advanced ovarian cancer who have been treated with three or more prior lines of chemotherapy. |
| FDBD01661 | Lenvatinib |
|
Antineoplastic Agents; Protein Kinase Inhibitors; Antineoplastic and Immunomodulating Agents; CYP3A4 Inhibitors; | Lenvatinib is indicated for the treatment of patients with locally recurrent or metastatic, progressive, radioactive iodine-refractory differentiated thyroid cancer. |
| FDBD01794 | Paritaprevir |
|
Antiinfectives for Systemic Use; Direct Acting Antivirals; Antivirals for Systemic Use; | For use in combination with ombitasvir, ritonavir and dasabuvir for the treatment of HCV genotype 1, and with ombitasvir and ritonavir for the treatment of HCV genotype 4. |
| FDBD01823 | Levobetaxolol |
|
; | |
| FDBD01835 | Lesinurad |
|
Gout Suppressants; Uricosuric Agents; Musculo-Skeletal System; Preparations Increasing Uric Acid Excretion; | For use in combination with a xanthine oxidase inhibitor; for the treatment of hyperuricemia associated with gout in patients who have not achieved target serum uric acid levels with a xanthine oxidase inhibitor alone. |
| FDBD01837 | Grazoprevir |
|
; | |
| FDBD01916 | cyclaniliprole |
|
Insecticide | Insecticide |
| FDBD01969 | cyromazine |
|
Insecticide | Insecticide |
| FDBD01975 | flucycloxuron |
|
Insecticide | Insecticide |
| FDBD02007 | dicyclanil |
|
Insecticide | Insecticide |
51 ,
6
| FRAGNAME | PDBID | SIMILIRITY | XSCORE | SMILE | HAC |
|---|---|---|---|---|---|
| 4n1u_ligand_frag_1.mol2 | 4n1u | 1 | -6.12 | C1CC1 | 3 |
| 4kin_ligand_frag_3.mol2 | 4kin | 1 | -6.08 | C1CC1 | 3 |
| 4kiq_ligand_frag_2.mol2 | 4kiq | 1 | -6.08 | C1CC1 | 3 |
| 3gfe_ligand_frag_2.mol2 | 3gfe | 1 | -6.06 | C1CC1 | 3 |
| 3iph_ligand_frag_4.mol2 | 3iph | 1 | -6.06 | C1CC1 | 3 |
| 3itz_ligand_frag_3.mol2 | 3itz | 1 | -6.06 | C1CC1 | 3 |
287 ,
29
