Responsive image

Common name

1-propylpiperidine

IUPAC name

1-propylpiperidine

SMILES

C(C)CN1CCCCC1

Common name

1-propylpiperidine

IUPAC name

1-propylpiperidine

SMILES

C(C)CN1CCCCC1

INCHI

InChI=1S/C8H17N/c1-2-6-9-7-4-3-5-8-9/h2-8H2,1H3

FORMULA

C8H17N

Responsive image

Common name

1-propylpiperidine

IUPAC name

1-propylpiperidine





Molecular weight

127.227

clogP

2.016

clogS

-1.760

Frequency

0.0041





HBond Acceptor

1

HBond Donor

0

Total Polar
Surface Area

3.24

Number of Rings

1

Rotatable Bond

2

Drug ID Common name Structure CAS Compound class Therapeutic area
FDBD00183 Ropivacaine Responsive image Anesthetics, Local; Anesthetics; Nervous System; Amides; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; Used in obstetric anesthesia and regional anesthesia for surgery.
FDBD00469 Cisapride Responsive image Gastrointestinal Agents; Anti-Ulcer Agents; Serotonin Receptor Agonists; Prokinetic Agents; Alimentary Tract and Metabolism; Drugs for Functional Gastrointestinal Disorders; Propulsives; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2A6 Inhibitors; CYP2A6 Inhibitors (strong); CYP2A6 Inhibitors (moderate); CYP2A6 Inducers; CYP2A6 Inducers (strong); CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
FDBD00950 Pimozide Responsive image Antipsychotic Agents; Dopamine Antagonists; Anti-Dyskinesia Agents; Nervous System; Psycholeptics; Diphenylbutylpiperidine Derivatives; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C19 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors; Combined Inhibitors of CYP3A4 and P-glycoprotein; Used for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment.
FDBD01030 Domperidone Responsive image Antiprotozoal Agents; Antiemetics; Dopamine Antagonists; Alimentary Tract and Metabolism; Antiparasitic Products, Insecticides and Repellents; Agents Against Protozoal Diseases; Drugs for Functional Gastrointestinal Disorders; Propulsives; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C8 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; For management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.
FDBD01270 Pipotiazine Responsive image Antipsychotic Agents; Phenothiazines; Nervous System; Psycholeptics; Phenothiazines With Piperidine Structure; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C19 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; For the maintenance treatment of chronic non-agitated schizophrenic patients.
FDBD01352 Iloperidone Responsive image Antipsychotic Agents; Adrenergic alpha-1 Receptor Antagonists; Nervous System; Psycholeptics; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors; Treatment of acute schizophrenia.
FDBD01418 Prucalopride Responsive image Alimentary Tract and Metabolism; Drugs for Constipation; Investigated for use/treatment in constipation, ileus, and pediatric indications.
FDBD01537 Lomitapide Responsive image Hypolipidemic Agents; Lipid Modifying Agents, Plain; Lipid Modifying Agents; Cardiovascular System; CYP3A4 Inhibitors; Used in homozygous familial hypercholesterolemia (HoFH) patients to reduce low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), apolipoprotein B (apo B), and non-high-density lipoprotein cholesterol (non-HDL-C).
FDBD01612 Eperisone Responsive image Musculo-Skeletal System; Muscle Relaxants, Centrally Acting Agents; Muscle Relaxants;
FDBD01620 Clocapramine Responsive image ;
12 , 2
FRAGNAME PDBID SIMILIRITY XSCORE SMILE HAC
4djh_ligand_3_16.mol2 4djh 1 -7.55 C(C(C)C)C[N@H+]1C[C@@H]([C@H](CC1)C)C 13
4djh_ligand_2_12.mol2 4djh 1 -6.73 CC[N@H+]1C[C@@H]([C@H](CC1)C)C 10
3i6m_ligand_3_9.mol2 3i6m 1 -6.59 C(C)C[NH+]1CCCCC1 9
4djh_ligand_1_4.mol2 4djh 1 -6.45 C[N@H+]1C[C@@H]([C@H](CC1)C)C 9
4djh_ligand_frag_5.mol2 4djh 1 -6.40 [NH2+]1C[C@@H]([C@H](CC1)C)C 8
2rcw_ligand_2_5.mol2 2rcw 1 -6.23 C(C)C[NH+]1CCCCC1 9
4gfd_ligand_3_34.mol2 4gfd 1 -6.20 C1CCC[NH+](C1)CCC(C)(C)C 12
2igy_ligand_3_266.mol2 2igy 1 -6.19 C(C)(C)CC[NH+]1CCCCC1 11
113 , 12