Common name
piperidin-4-ol
IUPAC name
piperidin-4-ol
SMILES
N1CCC(CC1)O
Common name
piperidin-4-ol
IUPAC name
piperidin-4-ol
SMILES
N1CCC(CC1)O
INCHI
InChI=1S/C5H11NO/c7-5-1-3-6-4-2-5/h5-7H,1-4H2
FORMULA
C5H11NO
Common name
piperidin-4-ol
IUPAC name
piperidin-4-ol
Molecular weight
101.147
clogP
0.735
clogS
-0.437
Frequency
0.0014
HBond Acceptor
1
HBond Donor
2
Total PolarSurface Area
32.26
Number of Rings
1
Rotatable Bond
0
| Drug ID | Common name | Structure CAS | Compound class | Therapeutic area |
|---|---|---|---|---|
| FDBD00375 | Haloperidol |
|
Antipsychotic Agents; Antiemetics; Dopamine Antagonists; Anti-Dyskinesia Agents; Butyrophenones; Antidyskinetics; Nervous System; Psycholeptics; Butyrophenone Derivatives; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; Combined Inhibitors of CYP3A4 and P-glycoprotein; | For the management of psychotic disorders (eg. schizophrenia) and delirium, as well as to control tics and vocal utterances of Tourette's syndrome (Gilles de la Tourette's syndrome). Also used for the treatment of severe behavioural problems in children with disrubtive behaviour disorder or ADHD (attention-deficit hyperactivity disorder). Haloperidol has been used in the prevention and control of severe nausea and vomiting. |
| FDBD00698 | Loperamide |
|
Antidiarrheals; Alimentary Tract and Metabolism; Antidiarrheals, Intestinal Anti-Inflammatory/antiinfective Agents; Antipropulsives; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C8 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; | For the control and symptomatic relief of acute nonspecific diarrhea and of chronic diarrhea associated with inflammatory bowel disease or gastroenteritis. Also used for reducing the volume of discharge from ileostomies. |
| FDBD01258 | Propericiazine |
|
Antipsychotic Agents; Adrenergic alpha-1 Receptor Antagonists; Phenothiazines; Nervous System; Psycholeptics; Phenothiazines With Piperidine Structure; | For use as adjunctive medication in some psychotic patients. Propericiazine (Pericyazine)is used for the control of residual prevailing hostility, impulsiveness and aggressiveness. |
| FDBD01342 | Bepotastine |
|
Mast Cell Stabilizers; | For the symptomatic treatment of itchy eyes (caused by IgE-induced mast cell degranulation) due to allergic conjunctivitis. |
4 ,
1
| FRAGNAME | PDBID | SIMILIRITY | XSCORE | SMILE | HAC |
|---|---|---|---|---|---|
| 2bvd_ligand_frag_0.mol2 | 2bvd | 1 | -6.26 | C1[NH2+]CCC(C1)O | 7 |
| 4l02_ligand_frag_6.mol2 | 4l02 | 1 | -6.17 | [NH2+]1CCC(CC1)O | 7 |
| 2yne_ligand_1_3.mol2 | 2yne | 1 | -6.15 | C1(CC[NH2+]CC1)O | 7 |
| 4caf_ligand_1_1.mol2 | 4caf | 1 | -6.15 | OC1CC[NH2+]CC1 | 7 |
| 4cae_ligand_1_4.mol2 | 4cae | 1 | -6.13 | C1(CC[NH2+]CC1)O | 7 |
| 4bbh_ligand_1_3.mol2 | 4bbh | 1 | -6.12 | [NH2+]1CCC(CC1)O | 7 |
| 4b11_ligand_1_3.mol2 | 4b11 | 1 | -6.10 | OC1CC[NH2+]CC1 | 7 |
| 4b13_ligand_1_3.mol2 | 4b13 | 1 | -6.10 | C1(CC[NH2+]CC1)O | 7 |
| 4v27_ligand_frag_2.mol2 | 4v27 | 1 | -6.08 | C1(CC[NH2+]CC1)O | 7 |
| 4b12_ligand_1_4.mol2 | 4b12 | 1 | -6.07 | C1(CC[NH2+]CC1)O | 7 |
398 ,
40
